Για καλύτερη έκβαση εκτός από το  

https://www.livemedia.com/krikoszoisammonia 

κατεβάσετε τους παρακάτω συνδέσμους  για βοήθεια στη διάγνωση,  στην εργαστηριακή προσέγγιση, στην θεραπευτική αντιμετώπιση,  στη διαιτητική παρακολούθηση, το πρωτόκολλο για  χειρουργικές επεμβάσεις που απαιτούν γενική αναισθησία και βίντεο με κινούμενα σχέδια (με ελληνικούς υπότιτλους) για μια από τις 6 διαταραχες του κύκλου ουρίας, την ανεπάρκεια Αργινάση 1.

Guidelines for the diagnosis & management of urea cycle disorders for all ages:   

• UCD Guidelines (Greek Translation)
• UCD_Guidelines (2019)
  

Dietary Handbook for UCD disorders Greek translation :

• UCD ASIEM Dietary Handbook (Greek Translation)

General Anaesthesia & UCD:   

• General Anesthesia & UCD Guidelines (Greek Translation)

Arginase 1 deficiency video Greek translation:

• Arginase-1 Deficiency Animation Video (Greek Translation)

Ακολουθούν παρακάτω χρήσιμοι επιπλέον σύνδεσμοι. Απαραίτητη η  επικοινωνία  με την ομάδα που σας παρακολουθεί 

Below are the latest guidelines from England for suspected hyperammonaemia in neonates and children.  Please consult your on call metabolic team for further guidance.

BIMDG Guidelines

The British Inherited Metabolic Disease Group have developed “child” guidelines for children and adolescents up to the end of puberty being managed on paediatric wards. These guidelines cover the diagnosis and early management of undiagnosed hyperammonaemia.

To access these guidelines click the link below, read the disclaimer and navigate to the Emergency Guidelines for Children Section. The guidelines can be found under “H”.

https://bimdg.org.uk/wp-content/uploads/2024/12/Hyperammonaemiaand_manage_2016_415469_09092016.pdf

RCPCH Guidelines

The Royal College of Paedeatrics and Child Health include a guidance for when and how to test ammonia levels in their guidelines titled “The management of children and young people with an acute decrease in conscious level”. 

To access these guidelines click the link below:

https://www.rcpch.ac.uk/resources/management-children-young-people-acute-decrease-conscious-level-clinical-guideline

Below are the latest guidelines from England for adults.  Please consult your on call metabolic team for further guidance.  

RCEM Guidelines

The Acute Behavioural Disturbance in Emergency Departments guidelines, published by the Royal College of Emergency Medicine, instucts healthcare professionals to conduct ammonia testing as part of investigations into decreased conciousness. Click the link below to access the guidelines:

https://rcem.ac.uk/wp-content/uploads/2023/10/Acute_Behavioural_Disturbance_in_Emergency_Departments_Oct2023_V2.pdf

Unsure of how to test for hyperammonaemia? Access the “Guidelines for the Investigation of Hyperammonaemia” from MetBioNet and contact your metabolic team if you require further guidance.

MetBioNet Guidelines

MetBioNet have published “Guidelines for the Investigation of Hyperammonaemia” which describe the differential diagnosis of hyperammonaemia, providing guidance to the non-specialist clinicians and laboratories on appropriate investigation, particularly with regards to inherited metabolic disorders.

To access these guidelines, click the link below to visit the MetBioNet best practice guidelines. Then scroll down the page until you reach the latest iteration of these guidelines.

https://metbio.net/best-practice-guidelines/

Krikos Zois is the Panhellenic Advocate for Inherited Metabolic Diseases in Greece. Its purpose is to provide scientific, social, financial and moral support to children suffering from inherited metabolic diseases and to their families.

Find out more: https://www.krikoszois.gr/